Crews, Fulton T.; Nixon, Kim
June 2003
Alcohol Research & Health;2003, Vol. 27 Issue 2, p197
Academic Journal
Recent research demonstrates that neural stem cells divide throughout life and give rise to new neurons, a process known as neurogenesis. This article addresses two principal questions concerning alcohol and adult neurogenesis: To what extent arc neurogenesis in the adult brain and the risk for alcoholism governed by similar factors? And to what extent and through what mechanisms do alcohol use and alcoholism affect adult neurogenesis? This article also discusses genetic and environmental influences on risk for alcoholism and on regulation of neurogenesis; the possibility that modulation of neurogenesis contributes to alcoholic pathology; and the evidence that alcohol disrupts neurogenesis in the adult brain, and the neurochemical processes by which this may occur.


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