Adenocarcinoid of the Appendix: Is Right Hemicolectomy Necessary? A Meta-analysis of Retrospective Chart Reviews

Varisco, Brian; McAlvin, Brian; Dias, James; Franga, Dion
July 2004
American Surgeon;Jul2004, Vol. 70 Issue 7, p593
Academic Journal
The purpose of this study was to determine the efficacy of simple appendectomy versus right hemicolectomy in the treatment of localized adenocarcinoid of the appendix. A literature review of retrospective chart reviews from 1966 to March 1, 2003, was performed. Outcomes of retrospective chart reviews were assessed on the basis of treatment modality. Meta-analysis of studies by determining odds ratios for appendectomy versus extended resection using the Hunter-Schmidt meta-analytic method was performed. One hundred patients from 13 studies met inclusion criteria. Seven per cent failure rate with appendectomy alone and 10 per cent with extended resection were observed [OR 1.9 (0.6-5.8); association X² 1.15, 1 df, P = 0.28]. Our data supports the use of appendectomy alone in localized cases of adenocarcinoid of the appendix provided there is no cecal involvement and the tumor's histology is low grade.


Related Articles

  • Goblet cell carcinoid of the appendix. Gordon, Richard; Burns, Karen; Friedlich, Martin // Canadian Journal of Surgery;Jun2005, Vol. 48 Issue 3, p251 

    The article presents a discussion on goblet cell carcinoid of the appendix. Three distinct histologic patterns have been identified in appendiceal carcinoids: the argentaffin-positive carcinoid, the non-argentaffin carcinoid, and the mucinous, goblet cell carcinoid. Therapy for carcinoids in the...

  • PSEUDOMYXOMA PERITONEI. Eisenstadt, H. B.; Wallace, S. M. // American Journal of Gastroenterology;Jul1963, Vol. 40 Issue 1, p82 

    A case of pseudomyxoma peritonei from an appendicial mucocele with rapid course and early demise forms the basis of this report. Pathological findings characterized the gelatinous muss as a Grade 1 adenocarcinoma according to the Woodruff-McDonald classification. In spite of only minor...

  • Ãœrolitiazisi taklit eden appendiks mukoseli. Dandin, Özgür; Ziya Balta, Ahmet; Sücüllü, İlker; Yücel, Ergün; Tevfik Özgan, Ediz; Yıldırım, Şükrü // Turkish Journal of Surgery / Ulusal Cerrahi Dergisi;2013, Vol. 29 Issue 2, p88 

    Appendiceal mucocele is a rare clinical condition that causes distension of the appendix lumen with mucus. It is only found in 0.1-0.3% of all appendectomy specimens. Twenty-five per cent of these cases are asymptomatic and incidentally discovered either during surgery or upon radiological...

  • Mucinous and Nonmucinous Appendiceal Adenocarcinomas: Different Clinicopathological Features but Similar Genetic Alterations. Kabbani, Wareef; Houlihan, Patrick S.; Luthra, Rajayalaksh; Hamilton, Stanley R.; Rashid, Asif // Modern Pathology;Jun2002, Vol. 15 Issue 6, p599 

    The genetic alterations of appendiceal carcinomas have not been reported in detail. We studied the clinicopathological factors and genetic alterations including microsatellite instability, p53 overexpression, and mutations of the K-ras proto-oncogene of 30 appendiceal adenocarcinomas, consisting...

  • Antibiotic Therapy Versus Appendectomy for Acute Appendicitis: A Meta-Analysis. Varadhan, Krishna K.; Humes, David J.; Neal, Keith R.; Lobo, Dileep N. // World Journal of Surgery;Feb2010, Vol. 34 Issue 2, p199 

    Antibiotic treatment has been shown to be effective in treating selected patients with acute appendicitis, and three randomized controlled trials (RCTs) have compared the efficacy of antibiotic therapy alone with that of surgery for acute appendicitis. The purpose of this meta-analysis of RCTs...

  • Moderne Therapie perityphlitischer Abszesse. Partecke, L.I.; Müller, A.; Kessler, W.; Diedrich, S.; Heidecke, C.-D.; Patrzyk, M.; Mensel, B. // Der Chirurg;Jul2014, Vol. 85 Issue 7, p622 

    Background: The recommendations for the treatment of an appendiceal mass are still controversial. The need for staged appendectomy is still under discussion. Patients and methods: In a retrospective study all patients with the diagnosis appendiceal mass (ICD 10 K35.32) treated in the surgical...

  • Role of Interval Appendectomy in the Management of Complicated Appendicitis in Children. Vane, Dennis W.; Fernandez, Nathanial // World Journal of Surgery;Jan2006, Vol. 30 Issue 1, p51 

    Introduction: The aim of this study was to ascertain the optimal treatment for children with complicated appendicitis. We reviewed an inception cohort of children with documented complicated appendicitis to develop criteria for interval appendectomy. We compared the outcomes of two treatments:...

  • The Efficacy of Postoperative Oral Antibiotics in Appendicitis: A Randomized Prospective Double-Blinded Study. Taylor, Edward; Berjis, Amir; Bosch, Theodore; Hoehne, Francesca; Ozaeta, Maria // American Surgeon;Oct2004, Vol. 70 Issue 10, p858 

    The conventional treatment of acute appendicitis is appendectomy followed by intravenous (IV) antibiotics until intraabdominal infection has resolved. It is controversial as to whether it is efficacious to add a course of oral antibiotics after cessation of IV antibiotics. All consenting...

  • Managing acute appendicitis. Benjamin, Irving S; Patel, A G // BMJ: British Medical Journal (International Edition);9/7/2002, Vol. 325 Issue 7363, p505 

    Editorial. Discusses ways to reduce negative appendectomies, or removal of a healthy appendix. Difficulty of diagnosing appendicitis; Use of an objective scoring system, such as the Alvarado system; Ultrasound and computed tomography examinations; Advantages of laparoscopic techniques in...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics