TITLE

Typhoid Fever in Travelers: Who Should Be Targeted for Prevention?

AUTHOR(S)
Steinberg, E. B.; Bishop, R.; Haber, P.; Dempsey, A. F.; Hoekstra, R. M.; Nelson, J. M.; Ackers, M.; Calugar, A.; Mintz, E. D.
PUB. DATE
July 2004
SOURCE
Clinical Infectious Diseases;7/15/2004, Vol. 39 Issue 2, p186
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
To clarify indications for typhoid vaccination, we reviewed laboratory-confirmed cases of typhoid fever reported to the United States Centers for Disease Control and Prevention between 1994 and 1999. To estimate the risk of adverse events associated with typhoid vaccination, we reviewed reports to the Vaccine Adverse Event Reporting System for the same period. Acute Salmonella enterica serotype Typhi infection was reported for 1393 patients. Of these patients, recent travel was reported by 1027 (74%), only 36 (4%) of whom reported having received a vaccination. Six countries accounted for 76% of travel-associated cases (India [30%I, Pakistan [13%I, Mexico [12%I, Bangladesh [8%I, The Philippines [8%I, and Haiti [5%I). For 626 travelers who traveled to a single country, the length of stay was ⩽1 week for 31 (5%), ⩽2 weeks for 100 (16%), ⩽3 weeks for 169 (27%), ⩽4 weeks for 232 (37%), ⩽5 weeks for 338 (54%), and ⩽6 weeks for 376 (60%). Reports of serious adverse events due to typhoid vaccination were very rare. Vaccination should be considered even for persons planning short-term travel to high-risk areas.
ACCESSION #
13726797

 

Related Articles

  • Ty21a Live Oral Typhoid Vaccine and Prevention of Paratyphoid Fever Caused by Salmonella enterica Serovar Paratyphi B. Levine, Myron M.; Ferreccio, Catterine; Black, Robert E.; Lagos, Rosanna; San Martin, Oriana; Blackwelder, William C. // Clinical Infectious Diseases;7/15/2007 Supplement, Vol. 45, pS24 

    In randomized, controlled field trials in Area Norte and Area Occidente of Santiago, Chile, 2 (Norte) or 3 (Occidente) doses of live oral typhoid vaccine Ty21a in enteric-coated capsules conferred protection against confirmed Salmonella enterica serovar Typhi disease (53% efficacy in Norte; 67%...

  • Conjugate vaccines for enteric fever: proceedings of a meeting organized in New Delhi, India in 2009. Podda, Audino; Saul, Allan; Arora, Rashmi; Bhutta, Zulfiqar; Sinha, Anju; Gaind, Rajni; Singhal, Tanu; Saha, Samir; Brooks, Abdullah; Martin, Laura B.; Amdekar, Yeshwant; Chitkara, Amar Jeet; Shieh, Mae; Kapur, Ambujam Nair; Chugh, Tulsi Das // Journal of Infection in Developing Countries;2010, Vol. 4 Issue 6, p404 

    Enteric fever is responsible for significant morbidity in South Asia and high prevalence of severe disease is seen in children under two years of age. Effective typhoid vaccines are available, but they cannot be used for children under two years of age and also have some limitations in older age...

  • TIP OF THE MONTH: Typhoid.  // Pulse;5/17/2007, Vol. 67 Issue 19, p76 

    The article provides information on the 70 changes to typhoid recommendations in May 2007, following a review of data by Health Protection Scotland published on the UK Travax website. One alteration is that typhoid immunization is no longer recommended for most of the countries that previously...

  • The Use of Typhoid Vaccines in Asia: The DOMI Experience. Ochiai, R. Leon; Acosta, Camilo J.; Agtini, Magdarina; Bhattacharya, Sujit K.; Bhutta, Zulfiqar A.; Canh Gia Do; Baiqing Dong; Xinguang Chen; Stanton, Bonita; Kaljee, Linda; Nyamete, Andrew; Galindo, Claudia M.; von Seidlein, Lorenz; DeRoeck, Denise; Jodar, Luis; Clemens, John D. // Clinical Infectious Diseases;7/15/2007 Supplement, Vol. 45, pS34 

    Background. Two currently licensed typhoid vaccines have been evaluated in Asia, yet few Asian countries have considered including typhoid vaccines in their vaccination programs. The Diseases of the Most Impoverished (DOMI) Program was initiated to provide evidence to decide on the introduction...

  • A method to generate recombinant Salmonella typhi Ty21a strains expressing multiple heterologous genes using an improved recombineering strategy. Yu, Bin; Yang, Mei; Wong, Ho; Watt, Rory; Song, Erwei; Zheng, Bo-Jian; Yuen, Kwok-Yung; Huang, Jian-Dong // Applied Microbiology & Biotechnology;Jul2011, Vol. 91 Issue 1, p177 

    Live attenuated Salmonella enterica serovar Typhi Ty21a (Ty21a) is an important vaccine strain used in clinical studies for typhoid fever and as a vaccine vector for the expression of heterologous antigens. To facilitate the use of Ty21a in such studies, it is desirable to develop improved...

  • New typhoid vaccine licensed.  // FDA Consumer;Mar1995, Vol. 29 Issue 2, p4 

    Discusses Typhim Vi (typhoid Vi polysaccharid vaccine), a single-injection typhoid vaccine for preventing typhoid fever, which was approved by the Food and Drug Administration in November 1994. Typhoid fever in the United States in 1992; Adverse reactions; More.

  • Single-dose typhoid fever vaccine.  // Modern Medicine;Apr95, Vol. 63 Issue 4, p27 

    Announces the availability of typhoid Vi polysaccharide vaccine for active immunizations against typhoid fever in persons who are two years of age and older. Persons who are strongly recommended for typhoid immunization.

  • Typhoid Fever: A Life-Threatening Illness Fever. Kumar, Vinod // New Indian Journal of Surgery;Jul-Sep2012, Vol. 3 Issue 3, p112 

    Typhoid fever, is a life-threatening illness associated with fever i.e. a systemic infection which is caused by Salmonella enteric serotype typhi (S. Typhi). It can also be caused by Salmonella paratyphi, a related bacterium that usually leads to a less severe illness. Typhoid fever also known...

  • A Randomised Trial Evaluating the Safety and Immunogenicity of the Novel Single Oral Dose Typhoid Vaccine M01ZH09 in Healthy Vietnamese Children. Tran Tinh Hien; Nguyen Thi Dung; Nguyen Thanh Truong; Ninh Thi Thanh Van; Tran Nguyen Bich Chau; Nguyen Van Minh Hoang; Tran Thi Thu Nga; Cao Thu Thuy; Pham Van Minh; Nguyen Thi Cam Binh; Tran Thi Diem Ha; Pham Van Toi; To Song Diep; Campbell, James I.; Stockwell, Elaine; Schultsz, Constance; Simmons, Cameron P.; Glover, Clare; Lam, Winnie; Marques, Filipe // PLoS Clinical Trials;Jul2010, Vol. 7 Issue 7, Special section p1 

    Background:The emergence of drug resistant typhoid fever is a major public health problem, especially in Asia. An oral single dose typhoid vaccine would have major advantages. M01ZH09 is a live oral single dose candidate typhoid vaccine containing Salmonella enterica serovar Typhi (Ty2 aroC-...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics