Prospects and strategies for malaria elimination in the Greater Mekong Sub-region: a qualitative study

Kaehler, Nils; Adhikari, Bipin; Cheah, Phaik Yeong; von Seidlein, Lorenz; Day, Nicholas P. J.; Paris, Daniel H.; Tanner, Marcel; Pell, Christopher
June 2019
Malaria Journal;6/20/2019, Vol. 18 Issue 1, pN.PAG
Academic Journal
Background: As malaria elimination becomes a goal in malaria-endemic nations, questions of feasibility become critical. This article explores the potential challenges associated with this goal and future strategies for malaria elimination in the Greater Mekong Sub-region. Methods: Thirty-two semi-structured interviews were conducted with policy makers (n = 17) and principal investigators (n = 15) selected based on their involvement in malaria prevention, control and elimination in the GMS. Interviews were audio-recorded and transcribed for qualitative content (thematic) analysis using QSR NVivo. Results: All respondents described current malaria control and elimination strategies, such as case detection and management, prevention and strengthening of surveillance systems as critical and of equal priority. Aware of the emergence of multi-drug resistance in the GMS, researchers and policy makers outlined the need for additional elimination tools. As opposed to a centralized strategy, more targeted and tailored approaches to elimination were recommended. These included targeting endemic areas, consideration for local epidemiology and malaria species, and strengthening the peripheral health system. A decline in malaria transmission could lead to complacency amongst funders and policy makers resulting in a reduction or discontinuation of support for malaria elimination. Strong commitment of policymakers combined with strict monitoring and supervision by funders were considered pivotal to successful elimination programmes. Conclusion: Against a backdrop of increasing anti-malarial resistance and decreasing choices of anti-malarial regimens, policy makers and researchers stressed the urgency of finding new malaria elimination strategies. There was consensus that multi-pronged strategies and approaches are needed, that no single potential tool/strategy can be appropriate to all settings. Hence there is a need to customize malaria control and elimination strategies based on the better surveillance data.


Related Articles

  • "People will say that I am proud": a qualitative study of barriers to bed net use away from home in four Ugandan districts. Monroe, April; Harvey, Steven A.; Lam, Yukyan; Muhangi, Denis; Loll, Dana; Kabali, Asaph Turinde; Weber, Rachel // Malaria Journal;2014, Vol. 13 Issue 1, p2 

    Background Despite increased access and ownership, barriers to insecticide-treated bed net (ITN) use persist. While barriers within the home have been well documented, the challenges to net use when sleeping away from home remain relatively unexplored. This study examines common situations in...

  • Severe malaria in Battambang Referral Hospital, an area of multidrug resistance in Western-Cambodia: a retrospective analysis of cases from 2006-2009. Chanthap Lon; Ans Timmermans; Nillawan Buathong; Samon Nou; Youry Se; Sitthy, Ngo; Soklyda Chann; Somporn Kraesub; Tippa Wongstitwilairoong; Walsh, Douglas S.; Tyner, Stuart; Fukuda, Mark; Callender, David; Sherwood, Jeffrey; Koy, Lenin; Char, Mengchour; Bethell, Delia; Saunders, David // Malaria Journal;2013, Vol. 12 Issue 1, p1 

    Background: Despite recent malaria containment and control efforts leading to reduced incidence, Cambodia remains endemic for both Plasmodium vivax and multidrug-resistant Plasmodium falciparum malaria. Little has been reported in the peer-reviewed literature regarding the burden of severe...

  • WHO calls for strengthening malaria elimination strategy, says 3.2 billion people still at risk.  // Express Healthcare;7/31/2015, p1 

    The article reports on the demand of the World Health Organization (WHO) to strengthen its strategy to eliminate and control the continuous risk of malaria globally. WHO regional director Poonam Khetrapal Singh mentions the organization's efforts on plasmodium falciparum (P falciparum) malaria...

  • A Study on Turkish and Lithuanian Young Adults' Perception of Values. Öcal, Adem; Yiğittir, Süleyman; Kyburiene, Laima; Navickiene, Gemma // Education & Urban Society;Mar2020, Vol. 52 Issue 3, p489 

    Whether on a national or an international level, it is important to settle how values are comprehended and justified. This study investigates how university students in Turkey and Lithuania make sense of certain values. The study has a pattern of a case study. The respondent selection was made...

  • In vitro selection of Plasmodium falciparum drug-resistant parasite lines. Nzila, Alexis; Mwai, Leah // Journal of Antimicrobial Chemotherapy (JAC);Mar2010, Vol. 65 Issue 3, p390 

    The in vitro selection of antimicrobial resistance in important pathogens can provide critical information on the genetic basis of drug resistance, and such information can be used to predict, anticipate and even contain the spread of resistance in clinical practice. For instance, the discovery...

  • Multiple Genetic Backgrounds of the Amplified Plasmodium falciparum Multidrug Resistance (pfmdr1) Gene and Selective Sweep of 184F Mutation in Cambodia. Sumiti Vinayak; Alam, Tauqeer; Sem, Rithy; Shah, Naman K.; Susanti, Augustina I.; Lim, Pharath; Muth, Sinuon; Maguire, Jason D.; Rogers, William O.; Fandeur, Thierry; Barnwell, John W.; Escalante, Ananias A.; Wongsrichanalai, Chansuda; Ariey, Frederick; Meshnick, Steven R.; Udhayakumar, Venkatachalam // Journal of Infectious Diseases;5/15/2010, Vol. 201 Issue 10, p1551 

    Background. The emergence of artesunate-mefloquine (AS+MQ)-resistant Plasmodium falciparum in the Thailand- Cambodia region is a major concern for malaria control. Studies indicate that copy number increase and key alleles in the pfmdr1 gene are associated with AS+MQ resistance. In the present...

  • What drives community adherence to indoor residual spraying (IRS) against malaria in Manhiça district, rural Mozambique: a qualitative study.  // Malaria Journal;2011, Vol. 10 Issue 1, p344 

    The article presents findings of a research conducted on examining the implementation process, reception and acceptability of indoor residual spraying (IRS) with dichlorodiphenyltrichloroethane (DDT) program in Manhiça district, Southern Mozambique. It mentions that National Malaria Control...

  • Pile sorts as a means of improving the quality of survey data: malaria illness symptoms. Brieger, William R. // Health Education Research;Jun1994, Vol. 9 Issue 2, p257 

    The article reports on the application of the pile sort technique to strengthen qualitative survey data on malaria. Pile sorts involve organizing a set of items (usually represented as names on cards) into piles based on their similarity or proximity. The research revealed that the grouping...

  • 'It is a journey of discovery': living with myeloma. de Wet, Rosslyn; Tandon, Anil; Augustson, Bradley; Joske, David; Lane, Heather // Supportive Care in Cancer;Jul2019, Vol. 27 Issue 7, p2435 

    Purpose: Although multiple myeloma (MM) is incurable, many people live with the disease for a number of years. Thus, understanding the effect of the disease and its therapies on the lives of those with MM is important. This qualitative study explores the impact of MM and its...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics