Clostridium difficile: a formidable foe
- Clostridium difficile: The new epidemic. Reed III, James F.; Edris, Bree A.; Eid, Sherrine; Molitoris, Allison // Internet Journal of Infectious Diseases;2009, Vol. 7 Issue 1, p9
Introduction: Currently Clostridium difficile associated disease (CDAD) is the most common cause of infectious diarrhea in hospitals and long-term care homes in the United States. We report prevalence of CDAD among selected DRG's and its impact on mortality rates, mean length of stay (LOS), and...
- Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity. Pépin, Jacques; Valiquette, Louis; Alary, Marie-Eve; Villemure, Philippe; Pelletier, Anick; Forget, Karine; Pépin, Karine; Chouinard, Daniel // CMAJ: Canadian Medical Association Journal;8/31/2004, Vol. 171 Issue 5, p466
Background: Recent reports suggest that Clostridium difficilecolitis may be evolving into a more severe disease. During the second half of 2002 we noted an increase in the number of patients with severe C. difficile-associated diarrhea (CDAD) in our institution. We describe cases of CDAD at our...
- Clostridium difficile-Associated Diarrhea: Epidemiological Data from Western Australia Associated with a Modified Antibiotic Policy. Thomas, Claudia; Stevenson, Mark; Williamson, D. James; Riley, Thomas V. // Clinical Infectious Diseases;12/15/2002, Vol. 35 Issue 12, p1457
The incidence of Clostridium difficile-associated diarrhea (CDAD) has increased dramatically in hospitals worldwide during the past 2 decades. In Western Australia, this increase was most obvious during the 1980s, when there was also an increase in the use of third-generation cephalosporin...
- Recurrent Clostridium difficile Colitis: Case Series Involving 18 Patients Treated with Donor Stool Administered via a Nasogastric Tube. Aas, Johannes; Gessert, Charles E.; Bakken, Johan S. // Clinical Infectious Diseases;3/1/2003, Vol. 36 Issue 5, p580
Clostridium difficile--associated diarrhea and colitis have emerged as major complications associated with use of systemic antimicrobials. In this study, the medical records for 18 subjects who received donor stool by nasogastric tube for recurrent C. difficile infection during a 9-year period...
- Clostridium difficile in association with sporadic diarrhoea. Brettle, R.P.; Poxton, I.R.; Murdoch, J. McC.; Brown, R.; Byrne, Marie D.; Collee, J.G. // British Medical Journal (Clinical Research Edition);1/23/1982, Vol. 284 Issue 6311, p230
Investigates the association of Clostridium (Cl) difficile with sporadic diarrhea. Assessment of patients with severe or moderately severe gastrointestinal illness; Detection of Cl difficile cytotoxin in feces; Administration of vancomycin.
- Persistence of an Endemic (Toxigenic) Isolate of Clostridium difficile in the Environment of a General Medicine Ward. Cohen, Stuart H.; Tang, Yajarayma J.; Rahmani, Darush; Silva Jr., Joseph // Clinical Infectious Diseases;6/1/2000, Vol. 30 Issue 6, p952
Investigates the epidemiology of Clostridium difficile-associated diarrhea (CDAD) to determine the strain identity of C. difficile isolates. Background on CDAD; Discovery of two predominant toxigenic clones of C. difficile; Role of environment and cross- transmission in the acquisition of CDAD.
- Decision rule for diagnosis of Clostridium difficile colitis. Huffman, Grace Brooke // American Family Physician;6/1/1997, Vol. 55 Issue 8, p2819
Presents a summary of the article `Predicting Clostridium difficile Stool Cytotoxin Results in Hospitalized Patients With Diarrhea,' by D.A. Katz, et al from the `Journal of General Internal Medicine' dated 1997. Patients that are likely to be affected by colitis; Scope of the study; Symptoms...
- Laboratory diagnosis of toxigenic Clostridium difficile by polymerase chain reaction: presence of toxin genes and their stable expression in toxigenic isolates from Japanese individuals. Karasawa, Tadahiro; Nojiri, Takashi; Hayashi, Yasuhiro; Maegawa, Tsuneo; Yamakawa, Kiyotaka; Wang, Xing Min; Nakamura, Shinichi // Journal of Gastroenterology;1999, Vol. 34 Issue 1, p41
Abstract: Clostridium difficile causes pseudomembranous colitis and antibiotic-associated diarrhea. The definitive diagnosis of C. difficile infection is finally accomplished by the isolation of toxigenic C. difficile. However, only a small number of Japanese clinical laboratories are able to...
- Cloudy peritoneal effluent and diarrhoea due to Clostridium difficile. Ribés-Cruz, José J.; González-Rico, Miguel; Juan-García, Isabel; Puchades-Montesa, M. Jesús; Torregrosa-Maicas, Isidro; Ramos-Tomás, Carmela; Solís-Salguero, Miguel A.; Tomás-Simó, Patricia; Tejedor-Alonos, Sandra; Zambrano-Esteves, Patricia; Miguel-Carrasco, Alfonso // Nefrologia;2014, Vol. 34 Issue 1, p130
A letter to the editor is presented commenting on diarrhoea due to Clostridium difficile.