TITLE

Is Azithromycin the First-Choice Macrolide for Treatment of Community-Acquired Pneumonia?

AUTHOR(S)
Halpern, Michael T.; Cifaldi, Mary A.
PUB. DATE
July 2004
SOURCE
Clinical Infectious Diseases;7/1/2004, Vol. 39 Issue 1, p144
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article focuses on the treatment choice for community-acquired pneumonia (CAP). The aim of this retrospective study was to compare outcomes, including mortality, for patients with CAP who were treated with either clarithromycin or azithromycin. However, there are a number of methodological problems with this study that may have biased the results, thus distorting the specified comparison. Clarithromycin was administered either as an intravenous infusion or as an oral tablet. In contrast, azithromycin was available for administration only as an oral tablet. Although the Pneumonia Patient Outcomes Research Team severity scores do not show significant differences between the 2 treatment groups, it is possible that patients thought to have more severe CAP were treated with clarithromycin, because this would permit continuation of intravenous therapy.
ACCESSION #
13602325

 

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