TITLE

Evidence to support RSV vaccination of the elderly?

AUTHOR(S)
Wilkinson, T. M. A.
PUB. DATE
June 2004
SOURCE
Thorax;Jun2004, Vol. 59 Issue 6, p511
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
RSV is an important respiratory pathogen in infants. There is increasing evidence that it also plays a significant role in seasonal morbidity of the elderly and those with underlying cardiopulmonary disease. This study followed two at risk populations for up to two winter seasons: a cohort of healthy elderly subjects and adults with cardiopulmonary disease. A third group of 625 patients admitted acutely into hospital with respiratory symptoms and who were also in either of these at risk groups was also studied. A PCR positive swab, detection of RSV in cell culture, or a fourfold rise in serum IgG to RSV envelope glycoproteins was taken as evidence of RSV infection. Overall, 130 RSV infections were identified over 2 years: 61 in the hospitalized group, 32 in the healthy elderly subjects, and 37 in those with cardiopulmonary disease.
ACCESSION #
13599837

 

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