TITLE

Budesonide/formoterol may be used for adjustable maintenance dosing in asthma

AUTHOR(S)
Simcock, D.
PUB. DATE
June 2004
SOURCE
Thorax;Jun2004, Vol. 59 Issue 6, p476
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This randomized, double blind/open two phase multicentre study, sponsored by Astra Zeneca, was conducted over 7 months to find out if asthma control was better when patients adjusted the maintenance dose of inhaled budesonide/formoterol according to asthma symptoms than when fixed dose (FD) regimens were used. In the open extension phase, those in the Symbicort adjustable maintenance dose arm were advised to reduce the number to one inhalation bd or to increase the number of inhalations to four bd for at least 7 days according to the frequency of reliever usage and nocturnal awakenings due to asthma. Symbicort FD significantly increased FEV1 compared with Seretide FD. Comparable improvements in FEY1 were observed with Symbicort AMD and Seretide FD.
ACCESSION #
13599829

 

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