TITLE

&alph;1-Antitrypsin deficiency 3: Clinical manifestations and natural history

AUTHOR(S)
Needham, M.; Stockley, R. A.
PUB. DATE
May 2004
SOURCE
Thorax;May2004, Vol. 59 Issue 5, p441
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
It has been long recognized that α 1 antitrypsin (AAT) deficiency is associated with an increase in clinical symptoms and diseases in several systems. Patients may be diagnosed with AAT deficiency after presentation with symptoms or through family screening of an index case. Close association between AAT deficiency and the development of emphysema was first described in the year 1963. The disease in these patients is usually of an earlier onset than in patients with chronic obstructive pulmonary disease.
ACCESSION #
13372518

 

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