Hemophagocytic Syndrome in a Patient with Acute Human Immunodeficiency Virus Infection

Castilletti, Concetta; Preziosi, Roberta; Bernardini, Giuliana; Caterini, Antonio; Gomes, Vito; Calcaterra, Silvia; Carletti, Fabrizio; Capobianchi, Maria R.; Armignacco, Orlando
June 2004
Clinical Infectious Diseases;6/15/2004, Vol. 38 Issue 12, p1792
Academic Journal
Scientists described a patient with advanced HIV infection and hemophagocytic syndrome (HPS) who did not respond to HAART and they underlined the fact that HPS caused by HIV infection alone has not been widely reported. It was observed that an acute HIV infection complicated by severe HPS that occurred in a 27-year-old Italian man. Results from examination of CSF were normal. A specimen from a laterocervical node biopsy showed small residual follicular areas and an intense histiocytic proliferation, with marked hemophagocytosis.


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