Management of Cryptococcal Meningitis with Extremely High Intracranial Pressure in HIV-Infected Patients

Hsin-Yun Sun; Chien-Ching Hung; Shan-Chwen Chang
June 2004
Clinical Infectious Diseases;6/15/2004, Vol. 38 Issue 12, p1790
Academic Journal
Cryptococcal meningitis develops in antiretroviral-naive patients with MDS at an estimated incidence of five percent to ten percent. However, the risk of brain herniation as a result of frequent lumbar punctures for elevated ICP has been a major concern among clinicians. Here, the case is presented on experience with frequent lumbar punctures and large-volume drainage of CSF in the management of extremely high ICP in HIV-infected patients who had cryptococcal meningitis. Death directly attributed to cryptococcal meningitis occurred in 2 patients.


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