TITLE

Topical Mupirocin and Catheter-Related Bacteremia

AUTHOR(S)
Allon, Michael
PUB. DATE
June 2004
SOURCE
Clinical Infectious Diseases;6/1/2004, Vol. 38 Issue 11, p1641
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The randomized study by D.W. Johnson and colleagues on the use of an investigational catheter lock solution (CLS) for the prevention of tunneled hemodialysis catheter-related bacteremia (CRB) demonstrated a substantial reduction in CRB by the application of topical mupirocin at the dialysis catheter exit site. Mupirocin has antibiotic activity only against gram-positive cocci. Although it is true that only 12.5% of our control patients with CRB had cultures that grew a gram-negative rod, the proportion of gram-negative bacterial infections among hemodialysis patients with CRB has been as high as 40%-45% in some reports.
ACCESSION #
13239313

 

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