Topical Mupirocin and Catheter-Related Bacteremia

Hartle II, J. Edward; Norfolk, Evan; Schwartzman, Michael; Yahya, Taher
June 2004
Clinical Infectious Diseases;6/1/2004, Vol. 38 Issue 11, p1641
Academic Journal
This article focuses on the use of an investigational catheter lock solution (CLS) for the prevention of tunneled hemodialysis catheter-related bacteremia. Results show a rate of tunneled hemodialysis catheter-related bacteremia after the use of CLS of 0.6 cases/1000 patient-days. This was compared with a rate of 5.6 cases/1000 patient-days found in the control population using a standard heparin lock. Other studies have reported a tunneled hemodialysis catheter-associated bacteremia rate of 0.2-0.5 cases/1000 patient-days.


Related Articles

  • Discrepancy between effects of carbapenems and flomoxef in treating nosocomial hemodialysis access-related bacteremia secondary to extended spectrum beta-lactamase producing klebsiella pneumoniae in patients on maintenance hemodialysis. Chih-Chao Yang; Shau-Hsuan Li; Feng-Rong Chuang; Chih-Hung Chen; Chih-Hsiung Lee; Jin-Bor Chen; Chien-Hsing Wu; Chien-Te Lee // BMC Infectious Diseases;2012, Vol. 12 Issue 1, p206 

    Background: Hemodialysis (HD) patients are susceptible to extended spectrum beta-lactamase (ESBL)-producing bacterial infections. Because the optimal treatment and clinical significance of ESBL-producing Klebsiella pneumoniae (ESBL-Kp) HD access-related bacteremia remain unclear, we conducted...

  • Blood transfusion during heparin-free hemodialysis. Sepulveda, Sebastian; Davis, Loretta; Schwab, Steve J. // Kidney International;Jun1997, Vol. 51 Issue 6, p2018 

    This article presents information on blood transfusion during heparin-free hemodialysis. The routine practice of hemodialysis requires anticoagulation to prevent thrombosis in the extracorporeal circuit. Heparin is used as the anticoagulant in the vast majority of treatments. In patients at risk...

  • More Evidence of Vancomycin Impotence. Deresinski, Stan // Infectious Disease Alert;Mar2007, Vol. 26 Issue 6, p63 

    Vancomycin was inferior to cefazolin in the treatment of MSSA bacteremia in chronic hemodialysis patients in a retrospective study.

  • Guidelines for Heparin Therapy. Genton, Edward // Annals of Internal Medicine;Jan74, Vol. 80 Issue 1, p77 

    Presents guidelines for heparin therapy. Anticoagulant mechanisms of heparin; Route of heparin administration; Counteraction of heparin effect.

  • Heparin.  // Reactions Weekly;12/5/2009, Issue 1281, p18 

    The article describes the case of a 38-year-old man who acquired skin necrosis while undergoing hemodialysis with heparin. Symptoms experienced by the patient who has chronic renal failure include ecchymosis and erythematous spots. It was decided to change to another anticoagulant but resulted...

  • R-Hirudin as Anticoagulant in Regular Hemodialysis Therapy: Finding of Therapeutic R-Hirudin Blood/Plasma Concentrations and Respective Dosages. Bucha, Elke; Nowak, Goetz; Czerwinski, Ralf; Thieler, Heinrich // Clinical & Applied Thrombosis/Hemostasis;Jul1999, Vol. 5 Issue 3, p164 

    Recently heparin-induced thrombocytopenia type II has been diagnosed more frequently and does not exclude hemodialysis patients. Up to now, recombinant hirudin is the only available anticoagulant showing no immunologic cross reactions with heparin. However, the use of r-hirudin in hemodialysis...

  • The clinical evaluation of low-dose heparin in haemodialysis: a prospective study using the heparin-coated AN69 ST membrane. Jacques Chanard; Sylvie Lavaud; Hervé Maheut; Isabelle Kazes; Fabien Vitry; Philippe Rieu // Nephrology Dialysis Transplantation;Jun2008, Vol. 23 Issue 6, p2003 

    Background. The AN69 ST haemodialysis membrane, a new membrane resulting from coating polyethyleneimine upon the polyacrylonitrile surface, binds heparin. In patients at risk of bleeding, a pilot study has demonstrated the efficient anticoagulant effect of this heparin-coated membrane. Study...

  • Heparin locking for central catheters: What is the optimal dose?  // CANNT Journal;Jul-Sep2004, Vol. 14 Issue 3, p27 

    Reveals that heparin has been described as the single most dangerous medication routinely used in hemodialysis. Results of a poll on the standard strength for catheter, published in the August 2003 "Nephrology Nursing Journal."

  • Sensitivity to heparin anticoagulant response in eosinophilic patients. Santoro, Antonio; Ferrari, Giuseppe; Zucchelli, Pietro // Kidney International Supplement;Mar1988, Issue 24, pS-84 

    Presents a study on the sensitivity to heparin anticoagulant response in eosinophilic patients. Signs of neutrophil and eosinophil aggregation and degranulation during hemodialysis; Determination of the laboratory methods and mathematical analysis of heparin half-life and the heparin-effect...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics