TITLE

Review: Vitamin E, vitamin C, and possibly coenzyme Q10 are ineffective for preventing or treating cardiovascular disease

PUB. DATE
May 2004
SOURCE
ACP Journal Club;May/Jun2004, Vol. 140 Issue 3, p73
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article presents the effectiveness of vitamin C, vitamin E, and coenzyme Q10 in preventing and treating cardiovascular disease (CVD). Studies in any language were selected if they were randomized controlled trials (RCTs) or systematic reviews evaluating vitamin C, vitamin E, or coenzyme Q10 in the prevention or treatment of CVD and assessing clinical outcomes. It was concluded that Vitamin E is not effective for preventing or treating cardiovascular disease. Evidence does not support vitamin C and is insufficient to support or refute the use of coenzyme Q10.
ACCESSION #
13221847

 

Related Articles

  • Role of vitamins in cardiovascular health and disease. Debreceni, Balazs; Debreceni, Laszlo // Research Reports in Clinical Cardiology;2014, Vol. 5, p283 

    Cardiovascular disease (CVD) is the leading cause of mortality around the world. The prevention of CVD is a main goal of health care. Vitamins, especially those with antioxidant potency, may have a role in the prevention of and therapy for CVD. Antioxidant vitamins, vitamin C, vitamin E, and...

  • Diet supplementation with vitamin E, vitamin C and β-carotene cocktail enhances basal neutrophil antioxidant enzymes in athletes. Tauler, P.; Aguiló, A.; Fuentespina, E.; Tur, J. A.; Pons, A. // Pflugers Archiv European Journal of Physiology;Mar2002, Vol. 443 Issue 5/6, p791 

    Exercise increases oxygen consumption and causes a disturbance of intracellular pro-oxidant-antioxidant homeostasis. Few data are available as to the cumulative effects of exercise on the antioxidant defenses of the neutrophil. We studied the effects of 90 days' supplementation with placebo or...

  • Effect of antioxidant therapy on collagen synthesis in corrosive esophageal burns. Günel, Engin; Çağlayan, Fatma; Çağlayan, Osman; Canbilen, Aydan; Tosun, Murat // Pediatric Surgery International;Jan2002, Vol. 18 Issue 1, p24 

    To investigate the efficacy of antioxidant therapy on collagen synthesis in corrosive esophageal burns, 110 Sprague-Dawley rats were divided into five groups of 22 animals each. A standard esophageal caustic burn was produced by 1 ml of 10% sodium hydroxide solution for the rats in groups B to...

  • Vitamins May Help Combat Alzheimer's Disease. Wooten, James M. // RN;Mar2004, Vol. 67 Issue 3, p88 

    Reports that vitamins may help combat Alzheimer's disease according to researchers from the U.S. Investigation on patients taking a combination of vitamins C and E; Assessment of the occurrence of dementia and AD; Survey on the vitamin intake of the study population.

  • Vitamin E: Two thumbs down.  // Cortlandt Forum;5/25/2005, Vol. 18 Issue 5, p14 

    The article presents information on developments related to research on vitamin E. In a double-blind, multinational trial, 7,030 people with CHD, peripheral arterial disease, prior stroke, or diabetes, plus one other CVD risk factor, were followed for a period of 10 years. This biggest and...

  • Clinical trial of adverse effect inhibition with glucosides of vitamin C and vitamin E in radiotherapy and chemotherapy. Masahiko, Koizumi; Tsunehiko, Nishimura; Tsutomu, Kagiya // Journal of Cancer Research & Therapeutics;Oct-Dec2005, Vol. 1 Issue 4, p239 

    The article evaluates ascorbic acid gucoside (AsAG) and atcopherol monoglucoside (TMG) in phase I-II trials, as side effect inhibitor in radiotherapy and chemotherapy. The study reveals that the oral administration of AsAG and TMG immediately after radiotherapy or chemotherapy prevented side...

  • Antioxidants do not prevent heart disease in high-risk individuals. Johnson, Kenneth H. // Journal of Family Practice;Oct2002, Vol. 51 Issue 10, p810 

    The article discusses research on the effect of antioxidants on heart disease. It references a study published in a 2002 issue of "Lancet." This placebo-controlled, double blind randomized trial was conducted in Great Britain. It concludes that antioxidant vitamins, such as vitamin E and C and...

  • Comparative Clinical Trial of Paracetamol alone and Vitamin C and E as an Add on Therapy in Patients Suffering From Primary Knee Osteoarthritis. Medhi, B.; Manpreet, S.; Deonis, X.; Aggarwal, S.; Pandhi, P.; Nagi, O. N. // JK Science;Jan-Mar2012, Vol. 14 Issue 1, p38 

    A randomized observational blind comparative clinical study was conducted to compare the antioxidant effect of vitamin C and E with paracetamol in patients of primary knee osteoarthritis. Subjects presenting with sign, symptoms of primary knee osteoarthritis were given paracetamol 1gm (n=50)...

  • The Antioxidants in Prevention of Cataracts Study: effects of antioxidant supplements on cataract progression in South India. Gritz, David C.; Srinivasan, M.; Smith, S. D.; Kim, U.; Lietman, T. M.; Wilkins, J. H.; Priyadharshiniv, B.; John, R. K.; Aravind, S.; Prajna, N. V.; Thulasiraj, R. Duraisami; Whitcher, J. P. // British Journal of Ophthalmology;Jul2006, Vol. 90 Issue 7, p847 

    Aim: To determine if antioxidant supplements (13 carotene and vitamins C and E) can decrease the progression of cataract in rural South India. Methods: The Antioxidants in Prevention of Cataracts (APC) Study was a 5 year, randomised, triple masked, placebo controlled, field based clinical trial...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics