TITLE

1-day quadruple therapy was not inferior to 7-day triple therapy for eradication of Helicobacter pylori infection in dyspepsia: COMMENTARY

AUTHOR(S)
Mukherjee, Debjani; Schwartz, Mark D.
PUB. DATE
May 2004
SOURCE
ACP Journal Club;May/Jun2004, Vol. 140 Issue 3, p66
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Dyspepsia is endemic and chronic. Most patients who are evaluated are diagnosed with nonulcer, or functional, dyspepsia. Systematic reviews support a modest benefit of H. pylori eradication in such patients, with perhaps 1 cure for every 15 patients treated. A Cochrane review concluded that the Helicobacter pylori test-and-treat approach may be less expensive and just as effective as endoscopy-based management in younger patients without alarm symptoms, showed similar efficacy of 1-day and standard 7-day treatment in achieving H. pylori eradication. Although dyspepsia symptoms improved, few patients had complete relief. If reproducible, a single-day course would likely have great advantages in cost, convenience, and adverse effects.
ACCESSION #
13221834

 

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