TITLE

Review: Inhaled corticosteroids slow the progression of airflow limitation in COPD: COMMENTARY

AUTHOR(S)
Greenstone, Michael
PUB. DATE
May 2004
SOURCE
ACP Journal Club;May/Jun2004, Vol. 140 Issue 3, p57
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Chronic obstructive pulmonary disease (COPD) is largely a disease of vulnerable smokers in whom the normal age-related decline in lung function is accelerated from a mean of 30 mL/y to 60 mL/y. Unlike asthma, the airflow obstruction and airway inflammation of COPD respond poorly to corticosteroids. COPD is now our fourth most common cause of death, and no drugs apart from oxygen alter the natural history of the disease. Furthermore, widespread introduction of high-dose inhaled corticosteroids (ICS) for all patients with COPD would be expensive given the prevalence of the disease and its long-term course.
ACCESSION #
13221817

 

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