April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA121
Academic Journal
Scientists have reported that following standard radiotherapy radiation induced apoptosis may be a time limited and volume dependent phenomenon and radiosensitive tumours should be surgically resected earlier than the more resistant ones. This article cites a study conducted to examine the relationship between the effect of radiation and expression of apoptosis regulating proteins. Results of the study suggest that among radioresistant tumours a combination of survivin(-)/p53(L) may be linked with greater tumour regression by apoptosis. Identification of these tumours' characteristics may lead to discovering their optimal treatment.


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