April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA121
Academic Journal
This article cites a study conducted to ascertain the role of methylation in colonic polyps, and to determine the clinicopathological correlates of methylation abnormalities in colonic precursor lesions. Results of the study suggest that hypermethylation and hypomethylation contribute separately to the process of carcinogenesis. It is likely that a proportion of hyperplastic polyps can progress to colorectal cancer.


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