April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA111
Academic Journal
Oesophageal clearance is an important mechanism of defence against gastro-oesophageal reftux disease (GORD). The study aims were to investigate the role of oesophageal clearance in patients with GORD and consider the effects of oesophageal lumen diameter and hiatus hernias (HH). Patients with pathological reflux on pH testing had a reduction in estimated oesophageal clearance reducing from 88% to 80%. No difference was found in estimated clearance between patients with and without oesophagitis. For a given volume of reflux a narrower lumen will cause the refluxate to rise further up the oesophagus.


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