April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA102
Academic Journal
Heme-oxygenase (HO) is the rate limiting enzyme in the metabolism of heme to form biliverdin, carbon monoxide, and free iron. HO-1 and HO-2 are expressed in normal colonic aoesophageal epithelium. HO-1 expression is increased in inflammatory bowel disease colorec cancer, and Barreft's oesophagus, which may represent a physiological response to oxidant stress in these conditions.


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