TITLE

INCREASED EXPRESSION OF HEME-OXYGENASE 1 IN INFLAMMATORY BOWEL DISEASE, COLORECTAL CANCER, AND BARRETT'S OESOPHAGUS

PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA102
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Heme-oxygenase (HO) is the rate limiting enzyme in the metabolism of heme to form biliverdin, carbon monoxide, and free iron. HO-1 and HO-2 are expressed in normal colonic aoesophageal epithelium. HO-1 expression is increased in inflammatory bowel disease colorec cancer, and Barreft's oesophagus, which may represent a physiological response to oxidant stress in these conditions.
ACCESSION #
13219211

 

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