April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA100
Academic Journal
Recent trials that hove looked at the efficacy of low molecular weight heparins (LMWH) in ulcerative colitis have found no benefit over placebo, which is in contrast to earlier trials with unfractionated heparin where high rates of remission were seen. were taken from a subset of patients with active ulcerative colitis from a multicentre placebo controlled trial of Innohep, a LMWH. Patients were randomised to receive either Innohep or placebo for six weeks, and rectal biopsies were taken before and after the course of treatment. Rectal biopsies were a1so obtained from patients.


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