TITLE

EOSINOPHILS LOCALISE TO NERVES IN PATIENTS WITH IBD THROUGH SPECIFIC NEURALLY EXPRESSED ADHESION MOLECULES AND CHEMOATTRACTANTS

PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA99
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The role of the eosinophil, which is a common inflammatory cell in inflamed gastrointestinal mucosa in inflammatory bowel disease (IBD) is uncertain. Using formolin fixed paraffin embedded tissue from patients who had previously undergone colonic resection for intractable IBD, the mechanisms of recruitment to enteric nerves were assessed. Specific neJratly expressed adhesion molecules and a specific eosinophil chen,oattractant appear to mediate localisation of eosinophils to nerves.
ACCESSION #
13219203

 

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