TITLE

MANAGEMENT OF LOW AND HIGH GRADE DYSPLASIA IN INFLAMMATORY BOWEL DISEASE: A GASTROENTEROLOGIST'S PERSPECTIVE AND CURRENT PRACTICE IN UK

PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA98
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Colonic dysplasia is a precursor to cotorectal cancer (CRC) in inflammatory bowel disease (IBD). There is a risk of progression of low and high grade dysplasia (LGD and HGD) to CRC. A study has been conducted to get an overview of the gastroenteroloist's perspective on various aspects of colonic dysplasia in IBD and to see the current management practice in Great Britain. It has been found that there are wide variations in the perceptions and management of LGD in IBD in Great Britain compared to HGD where there seems to be a more uniform agreement.
ACCESSION #
13219197

 

Related Articles

  • Thiopurines prevent advanced colorectal neoplasia in patients with inflammatory bowel disease. Fiona D M van Schaik // Gut;Feb2012, Vol. 61 Issue 2, p235 

    BACKGROUND AND AIMS: Previous studies have suggested a chemopreventive effect of 5-aminosalicylic acid (5-ASA) therapy in patients with inflammatory bowel disease (IBD). This effect has not been reported in IBD patients using thiopurines. We investigated the association between thiopurine or...

  • USE OF 5-ASA IS ASSOCIATED WITH DECREASED RISK OF DYSPLASIA AND COLON CANCER IN ULCERATIVE COLITIS.  // Gut;Apr2004 Supplement 3, Vol. 53, pA119 

    Risk factors for dysplasia and colon cancer (CRC) in ulcerative colitis (UC) include— duration and extent of disease, younger age of diagnosis, family history of CRC, and primary sclerosing cholangitis (PSC). Mesalazine (5-ASA) is a mainstay of UC treatment and has been suggested to have...

  • Colonoscopic surveillance improves survival after colorectal cancer diagnosis in inflammatory bowel disease. Lutgens, M. W. M. D.; Oldenburg, B.; Siersema, P. D.; van Bodegraven, A. A.; Dijkstra, G.; Hommes, D. W.; de Jong, D. J.; Stokkers, P. C. F.; van der Woude, C. J.; Vleggaar, F. P. // British Journal of Cancer;11/17/2009, Vol. 101 Issue 10, p1671 

    Background:Colonoscopic surveillance provides the best practical means for preventing colorectal cancer (CRC) in inflammatory bowel disease (IBD) patients. Strong evidence for improved survival from surveillance programmes is sparse.Method:The aim of this study was to compare tumour stage and...

  • The management of dysplasia associated with ulcerative colitis: colectomy versus continued surveillance. Friedlich, Martin S.; Guindi, Maha; Stern, Hartley S. // Canadian Journal of Surgery;Jun2004, Vol. 47 Issue 3, p212 

    The article focuses on the management of dysplasia associated with ulcerative colitis (UC). Colectomy versus continued surveillance in patients with longstanding UC is a challenging decision. Several factors must be considered. Often such patients have quiescent disease, making the prospect of...

  • Molecular Pathways Underlying IBD-Associated Colorectal Neoplasia: Therapeutic Implications. Goel, Gati A.; Kandiel, Ahmed; Achkar, Jean Paul; Lashner, Bret // American Journal of Gastroenterology;Apr2011, Vol. 106 Issue 4, p719 

    Chronic inflammatory diseases, depending upon the duration and severity, are frequently associated with an increased risk of developing cancer. A classic paradigm is the enhanced risk of colorectal cancer (CRC) in patients with inflammatory bowel disease (IBD). Carcinogenesis is a multifactorial...

  • Inflammatory Bowel Disorders. Burroughs, Andrew; Keshav, Satish; Moss, Steven // Current Medical Literature: Gastroenterology;2012, Vol. 31 Issue 2, p49 

    The article discusses a number of studies relating to inflammatory bowel disorders. The first two highlight the increased risk of non-melanoma skin cancers in patients with inflammatory bowel disease (IBD) who are treated with thiopurine drugs. The third investigates the risk of colorectal...

  • Mesalamine protects against colorectal cancer in inflammatory bowel disease. Tang, Jeffrey; Sharif, Omar; Chetan Pai; Silverman, Ann L.; Pai, Chetan // Digestive Diseases & Sciences;Jun2010, Vol. 55 Issue 6, p1696 

    Background: Individuals with inflammatory bowel disease (IBD) are at increased risk of developing colorectal cancer (CRC) compared with the general population. Previous studies show this risk is strongly associated with dysplasia, extent of disease, duration of disease, and degree...

  • Cancer in inflammatory bowel disease. Jianlin Xie; Itzkowitz, Steven H. // World Journal of Gastroenterology;1/21/2008, Vol. 14 Issue 3, p378 

    Patients with long-standing inflammatory bowel disease (IBD) have an increased risk of developing colorectal cancer (CRC). Many of the molecular alterations responsible for sporadic colorectal cancer, namely chromosomal instability, microsatellite instability, and hypermethylation, also play a...

  • Risk Factors for Colorectal Neoplasia in Inflammatory Bowel Disease: A Nested Case–Control Study From Copenhagen County, Denmark and Olmsted County, Minnesota. Jess, Tine; Loftus, Edward V.; Velayos, Fernando S.; Winther, Karen V.; Tremaine, William J.; Zinsmeister, Alan R.; Scott Harmsen, W.; Langholz, Ebbe; Binder, Vibeke; Munkholm, Pia; Sandborn, William J. // American Journal of Gastroenterology;Apr2007, Vol. 102 Issue 4, p829 

    OBJECTIVES: Population-based data on risk factors and protective factors for colorectal dysplasia and cancer in patients with inflammatory bowel disease (IBD) are sparse. We conducted a nested case–control study of such factors in two well-described IBD cohorts from Copenhagen County,...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics