April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA97
Academic Journal
The article presents a randomised trial of fibre and non-stimulant osmotic laxative in patients with constipation and distal ulcerative colitis (UC) with assessment of pre- and post-treatment symptom response and colonic transit. Consecutive patients with active or quiescent distal UC were screened for constipation using the Thompson criteria. The study revealed that colonic transit in the majority of patients with distal UC and constipation is normal. A minority have delayed transit in the left colon and rectosigmoid. There appears to be normal motility on the right side of the colon.


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