April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA97
Academic Journal
Steroid resistance in ulcerative colitis (UC) presents a difficult clinical challenge, with few available therapeutic options other than colectomy. Basiliximab is a chimeric monoclonal antibody to the interleukin-2 receptors. This has potential as new treatment for this condition. The article presents a study of basiliximab treated patients with steroid resistant UC. The study revealed that treatment with basiliximab in combination with steroids achieved an improvement in 95% and remission in 70% of patients with moderate steroid resistant UC.


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