April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA95
Academic Journal
The article investigates clinical and functional significance of Vitamin D receptor (VDR) polymorphisms in inflammatory bowel disease. For the study purpose genomic DNA was extracted from 218 inflammatory bowel disease (IBD) patient and also included ulcerative colitis, Crohn's disease (CD) and indeterminate colitis patients. It has been observed that VDR polymorphisms have downstream effects upon target gene expression and clinical significance in IBD. The Fok1 polymorphism has links to colitis associated colorectal neoplasia.


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