TITLE

IMPROVEMENT IN RENAL FUNCTION AFTER SWITCH TO SIROLIMUS

PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA93
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article investigates effect of sirolimus on renal function, following liver transplantation and long term immunosuppression with tacrolimus and cyclosporin. Study was performed on 17 liver transplant recipients, who had their calcineurin inhibitor substituted with sirolimus monotherapy at 6-83 months. The study showed that 69% of patients showed an improvement in serum creotinine 2 years after changing to sirolimus. There was a high incidence of side effects causing discontinuation of sirolimus but at doses now regarded as excessive.
ACCESSION #
13219179

 

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