TITLE

FIVE YEAR FOLLOW UP OF IMMUNE SUPPRESSION WITH SIROLIMUS FOR LIVER TRANSPLANTATION

PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA93
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article analyzes data of five year follow up of immune suppression with sirolimus for liver transplantation. Data of patients was reviewed to determine survival, outcome after transplantation for hepatocellular carcinoma (HCC), changes in renal function, effect on hepatitis C, and side effects. Patients given sirolimus instead of a calcineurin inhibitor for their primary immunosuppression have better renal function after 5 years and improved survival if transplanted for HCC. There may be slower progression of hepatitis C related fibrosis. Problems related to chronic rejection or other long term side effects were not observed.
ACCESSION #
13219178

 

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