TITLE

PREVALENCE OF GENETIC HAEMOCHROMATOSIS AND IRON OVERLOAD AMONG PATIENTS ATTENDING RHEUMATOLOGY AND JOINT REPLACEMENT CLINICS

PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA87
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Genetic haemochromatosis (GH) is a common and underdiagnosed disorder, particularly affecting Celtic populations. Arthropathy is a common clinical expression. The aim of our study was to estimate the frequency of the HFE mutations and iron overload among patients attending the joint replacement clinic and new patients referred to the rheumatology clinic at our hospital and compare with a local control population. The C282Y carrier frequency is significantly higher in patients offending the rheumatology and joint replacement clinics than controls. Screening of these patients for GH should be considered.
ACCESSION #
13219154

 

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