April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA86
Academic Journal
Hepatic schistosomiasis is an immunoregulatory disease characterized by elaboration of various cytokines and is frequently associated with anaemia. Hepatic schistosomiasis is associated with increased production of IL-1, and TNF. Only TNF seems to play a role in the suppression of late erythropoiesis, disturbance of iron status, and development of anaemia in this disease. This immune mediated mechanism has to be considered in the management of anaemia in patients with SHF.


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