April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA85
Academic Journal
Chronic liver disease is associated with renal dysfunction perhaps related to increased activation of the renin-angiotensin system (RAS). Two RAS polymorphisms are the angiotensin converting enzyme (ACE) gene (DD genotype associated with increased activity of ACE) and the angiotensinogen gene. The aim of this study was to investigate whether these polymorphisms were related to renal dysfunction in patients with chronic liver disease. The study concludes that polymorphisms associated with increased RAS expression were not associated with renal dysfunction.


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