April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA82
Academic Journal
Steatosis is a frequent histological finding in chronic hepatitis C virus (HCV); however, the pathophysiology of steatosis and its role in disease progression is controversial. It has been suggested that steatosis is associated with genotype 3 and that steatosis could accelerate progression of fibrosis. However most studies of hepatitis C associated steatosis have been performed in areas where genotype 1 predominates and are limited by having small numbers of genotype 3. To address this researchers studied 221 patients with liver biopsy proven chronic HCV, 107 of whom were infected with genotype 3. Age, alcohol consumption, body mass index and HCV genotype were correlated with steatosis and fibrosis.


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