Praveen, E.; Caims, A.; Ali, F.; Duane, P. D.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA76
Academic Journal
Recent RCT data have demonstrated significant benefits of a 72 hour IV omeprazole infusion, for patients undergoing endoscopic haemostasis for bleeding peptic ulcers. This article presents a study to assess the effectiveness of IV omeprazole on outcomes, a retrospective audit of all patients receiving this therapy was audited. This group was compared to alt those who received endoscopic therapy alone. Patients receiving IV omeprazol had lower rates of rebleeding, surgical intervention and mortality. The transfusion requirements and hospital stay were significantly reduced.


Related Articles

  • The Risk of Peptic Ulcer Bleeding Mortality in Relation to Hospital Admission on Holidays: A Cohort Study on 8,222 Cases of Peptic Ulcer Bleeding. Tsoi, Kelvin K F; Chiu, Philip W Y; Chan, Francis K L; Ching, Jessica Y L; Lau, James Y W; Sung, Joseph J Y // American Journal of Gastroenterology;Mar2012, Vol. 107 Issue 3, p405 

    OBJECTIVES:Urgent endoscopic intervention is important in the management of patients with peptic ulcer bleeding (PUB). Hospital admission on Sundays or on public holidays may be associated with an increased mortality. This study sets to investigate whether mortality among patients with PUB...

  • Effect of scheduled second therapeutic endoscopy on peptic ulcer rebleeding: a prospective randomised trial. Chiu P W Y; Lam C Y W; Lee S W; Kwong K H; Lam S H; Lee D T Y; Kwok S P Y // Gut;Oct2003, Vol. 52 Issue 10, p1403 

    Aim: Recurrent bleeding after initial haemostasis is an important factor that directly relates to the outcome in the management of peptic ulcer bleeding. Conflicting reports have been published concerning the effectiveness of scheduled second therapeutic endoscopy on ulcer rebleeding. We...

  • Laparoscopic treatment of gastroduodenal perforations: comparison with conventional surgery. Kirshtein, B.; Bayme, M.; Mayer, T.; Lantsberg, L.; Avinoach, E.; Mizrahi, S. // Surgical Endoscopy;Nov2005, Vol. 19 Issue 11, p1487 

    Background: Laparoscopic techniques have been proposed as an alternative to open surgery for the treatment of peptic ulcer perforation. This study compared the outcome of laparoscopic and open approaches for the repair of gastroduodenal perforations.Methods: A...

  • The Effect of Endoscopic Therapy in Patients Receiving Omeprazole for Bleeding Ulcers with Nonbleeding Visible Vessels or Adherent Clots. Sung, Joseph J.Y.; Chan, Francis K.L.; Lau, James Y.W.; Man-Yee Yung; Wai-Keung Leung; Wu, Justin C.Y.; Ng, Enders K.W.; Sydney Chung, S.C. // Annals of Internal Medicine;8/19/2003, Vol. 139 Issue 4, p237 

    Focuses on the effect of endoscopic therapy in patients receiving omeprazole for bleeding ulcers with nonbleeding visible vessels or adherent clots. Effect of endoscopic treatment on bleeding from peptic ulcers; Different approaches of treating bleeding from a peptic ulcer patients; Method of...

  • Factores asociados con complicaciones posoperatorias y mortalidad en úlcera péptica perforada. Montalvo-Javé, Eduardo Esteban; Corres-Sillas, Omar; Athié-Gutiérrez, César // Cirugia y Cirujanos;mar/abr2011, Vol. 79 Issue 2, p141 

    Background: Elective surgery for uncomplicated peptic ulcer has shown a significant decrease; however, complications such as perforation and obstruction persist and require urgent surgical management. The aim of this study was to identify factors associated with early postoperative complications...

  • Management Strategies, Early Results, Benefits, and Risk Factors of Laparoscopic Repair of Perforated Peptic Ulcer. Lunevicius, Raimundas; Morkevicius, Matas // World Journal of Surgery;Oct2005, Vol. 29 Issue 10, p1299 

    The primary goal of this study was to describe epidemiology and management strategies of the performed duodenal ulcer, us well as the most common methods of laparoscopic performed duodenal ulcer repair. The secondary goal was to demonstrate the value of prospective and retrospective studies...

  • Risk Factors Predicting Morbidity and Mortality in Peptic Ulcer Perforation at Maharaj Nakorn Chiangmai Hospital. Sukpromson, Choopong; Rerkasem, Kittipan; Sumitsawan, Somsak // Thai Journal of Surgery;Apr-Jun2006, Vol. 27 Issue 2, p68 

    Background: Peptic ulcer perforation (PUP) is one of the important problems in Maharaj Nakorn Chiangmai Hospital due to high morbidity and mortality. If the risk factors of these outcomes are identified, modification of these risk factors may improve the outcomes. This study was conducted to...

  • Immediate Results of Omentopexy in Perforated Duodenal Ulcer: A Study of 186 Cases. Gujar, Nishikant; Awati, Jilani; Mudhol, Sajid; Contractor, Salahuddin; Choudhari, Ravikumar; Garag, Sushila // Al Ameen Journal of Medical Sciences;2012, Vol. 5 Issue 1, p29 

    Aim of the Study: The study was conducted to determine short term results in view of associated diseases, complications, mortality and hospital stay in patients with duodenal ulcer perforation treated by omentopexy. Main Findings: Age of patients range from 15 to 85 years; mean age was 45.58...

  • Can AIMS65 Save the Endoscopists from Midnight Calls? Joon Sung Kim; Byung-Wook Kim // Clinical Endoscopy;Nov2015, Vol. 48 Issue 6, p459 

    The author discusses the study which examines the usefulness of AIMS65 score to portend mortality in patients having non-variceal upper gastrointestinal bleeding (NVUGIB). He mentions that the findings recommends that AIMS65 score was superior compared to the Rockall score in projecting...


Read the Article


Sign out of this library

Other Topics