TITLE

FISH OIL AND ANTIOXIDANTS ALTER COMPOSITION AND FUNCTION OF CIRCULATING MONONUCLEAR CELLS IN CROHN'S DISEASE

AUTHOR(S)
Trebble, T. M.; Calder, P. C.; Wootton, S. A.; Arden, N. K.; Mullee, M. A.; Fine, D. R.; Stroud, M. A.
PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA74
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Cytokine production by peripheral blood mononuclear cells (PBMC) may contribute towards altered bone turnover and other extra-intestinal manifestations of Crohn's disease (CD). Dietary supplementation with eicosapentaenoic and docosahexaenoic acid rich fish oil influences cytokine production by PBMC in healthy subjects and show therapeutic effects in CD. In this study, researchers therefore investigated the effect of fish oil on PBMC incorporation of fatty acids and production of tumour necrosis factor-α, interferon-γ and prostaglandin E2 in CD.
ACCESSION #
13219106

 

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