Daley, A. C.; Croft, N.; Randall, R.; Kelly, P.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA72
Academic Journal
Response to oral vaccination is usually assessed by analysis of peripheral blood, but this may not represent mucosal immune responses. Researchers in a study report a comparison of systemic and mucosal immune responses following oral vaccination. Measurement of specific immunoglobulin A responses in whole gut lavage fluid is a sensitive method of assessing the mucosal immune response to oral vaccination. Negative antibody-secreting cell and serological results may not imply that an individual has failed to respond to oral vaccination.


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