Thurairajah, P.; Clark, D.; Thompson, I. W.; Allison, M. C.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA70
Academic Journal
The IgA anti-tissue transglutaminase (TTG) assay is becoming the preferred initial screening test for celiac disease because it is less labor intensive than the more specific endomysial antibody assay (EMA). The study examined the clinical impact of TTG before and after a recalibration of the TTG assay by its manufacturer. The study reviewed duodenal biopsies performed for patients with positive TTG assays during six months of 2001 and six months of 2002. Histological results were correlated with TTG titre and EMA results. A positive TTG was taken as a result exceeding 10 units/ml.


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