TITLE

SELDI-MS PROTEIN PROFILING CAN DIFFERENTIATE TUMOUR FROM NORMAL COLORECTAL TISSUE

AUTHOR(S)
Lennon, A. M.; Stuart, D.; Tan, A. C.; Fox, E.; Sheahan, K. S.; Hyland, J. M.; O'Donoghue, D. P.; Brown, B.
PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA68
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a study that uses Surface enhanced laser desorption ionisation mass spectrometry (SELDI-MS) to examine the feasibility of differentiating tumor from normal colorectal tissue. SELDI-MS is a technique which has been used to study proteomic patterns in cell lines, tumor material, and serum samples. 210 proteomic spectra were generated from 95 normal and tumor tissue samples. Ciphergen Biomarker Wizard was used to identify significant peptide peaks. In-house decision analysis tree was then used to differentiate the two sample types.
ACCESSION #
13219081

 

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