Lennon, A. M.; Stuart, D.; Tan, A. C.; Fox, E.; Sheahan, K. S.; Hyland, J. M.; O'Donoghue, D. P.; Brown, B.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA68
Academic Journal
The article presents a study that uses Surface enhanced laser desorption ionisation mass spectrometry (SELDI-MS) to examine the feasibility of differentiating tumor from normal colorectal tissue. SELDI-MS is a technique which has been used to study proteomic patterns in cell lines, tumor material, and serum samples. 210 proteomic spectra were generated from 95 normal and tumor tissue samples. Ciphergen Biomarker Wizard was used to identify significant peptide peaks. In-house decision analysis tree was then used to differentiate the two sample types.


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