TITLE

MICROBIAL DIVERSITY AND CARBOHYDRATE EXPRESSION IN HEALTHY AND NEOPLASTIC COLONIC TISSUE

AUTHOR(S)
Hope, M.; Hold, G. L.; Kain, R.; El-Omar, E. M.
PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA68
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a study to define mucosal bacterial populations in healthy and neoplastic human colonic tissue and to correlate this with carbohydrate expression. Colonic microbiota can influence and modulate the colonic neoplastic process. The microbiota also affect colonic carbohydrate expression, which itself is altered by the neoplastic process. Fecal samples and mucosal biopsies from 6 anatomically distinct colonic sites were taken from two healthy individuals. Bacterial populations were compared using 16S rDNA sequencing and DGGE--a microbial fingerprinting technique.
ACCESSION #
13219080

 

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