Lewis, S. J.; Burmeister, S.; Cohen, S.; Brazier, J.; Awashi, A. K.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA68
Academic Journal
The article presents a study to determine if the incidence of antibiotic associated diarrhea could be reduced by oral oligofructose. Antibiotic associated diarrhea, especially caused by Clostridium difficile infection, leads to significant morbidity and mortality in elderly patients. A high fecal bifidobacterial concentration is thought to be a major factor in colonization resistance against invading pathogens. Oligofructose is selectively metabolized by bifidobacteria and results in a marked increase in their numbers.


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