Lennon, A. M.; Sturat, D.; Tan, A. C.; Sheahan, K. S.; O'Donoghue, D. P.; Brown, B.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA67
Academic Journal
Surface enhanced laser desorption ionisation mass spectrometry (SELDI-MS) is a technique which has been used to study proteomic patterns. The article presents a study which aims to determine the sensitivity of SELDI-MS in differentiating two different cell lines. The study demonstrates the potential of SELDI-MS to differentiate two different cell lines with a high level of sensitivity and specificity. 198 protein peaks were generated from 13 cell line extracts. Ciphergen Biomarker Wizard was used to identify significant peaks and an in-house decision analysis tree was used to differentiate the two sample types.


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