TITLE

ANTIMICROBIAL ACTIVITY OF β DEFENSINS AGAINST CRYPTOSPORIDIUM PARVUM

AUTHOR(S)
Zaalouk, T. K.; Bajaa-Elliott, M.; George, J. T.; McDonald, V.
PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA65
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article studies the antimicrobial activity of β defensins against cryptosporidium parvum. The mucosal surface of the gastrointestinal tract (GI) is continuously exposed to a vast array of exogenous agents, which include dietary antigens, commensal flora, and potential pathogens. There is accumulating evidence that besides forming a physical barrier, the intestinal epithelium is also an active participant in host innate defence via the production of antimicrobial peptides, cytokines, and chemokines. Defensins are small cationic antimicrobial peptides that are increasingly being recognised as important effectors in innate immunity.
ACCESSION #
13219069

 

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