Newsome, P. N.; Dalakos, E.; Hayes, P. C.; Harrison, D. J.; Plevris, J. N.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA63
Academic Journal
The article presents a study stating that serum from patients with acute liver failure decreases T cell differentiation of human stem cells. Previous studies have shown that CD34 stem cells are mobilised in response to certain types of human liver injury, and that ability to mobilise such cells is associated with an improved clinical outcome. However the effect of human liver injury serum on isolated human stem cells in terms of necrosis and differentiation profile (hepatocytic and haematopoietic) is poorly understood.


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