Talwar, V.; Wurm, P.; de Caestecker, J. S.; Gershlick, A. H.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA62
Academic Journal
The article presents a controlled clinical trial of lansoprazole to test the gastro-oesophageal reflux (GOR) related pain in ischaemic heart disease (IHD). GOR and IHD commonly coexist. IHD patients may mistake GOR induced pain for cardiac pain. lntra-oesophageal acid can trigger angina or reduce exertional angina threshold. Such an effect of GOR might be likely in patients with rest or night pain. The study reports a double blind controlled crossover study of lansoprazole (PPI) in IHD patients.


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