Misra, N.; Hardwick, R. H.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA60
Academic Journal
The focus of this article is to investigate which geographical areas have the highest incidence rates of oesophageal adenocarcinoma in the world. Incidence data for oesophageal adenocarcinoma were retrieved from the Cancer in Five Continents Volume VIII database, a database comprising incidence data for all neoplastic lesions from 252 cancer registries worldwide, compiled by the International Association of Cancer Registries (IACR). Incidence data are for the period 1993-97. Cumulative lifetime risk was calculated for each registry, which describes the percentage risk of contracting oesophageal adenocarcinoma by the age of 79. According to the IACR, Scotland, England, and Northern Ireland have the highest incidence rates for oesophageal adenocarcinoma in the world. An examination of changing social trends in these populations, such as the incidence of obesity, reflux disease, cigarette, and alcohol use, may give epidemiological clues to the aetiology of this increasingly common disease.


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