Gupta, S.; Amaout, A.; Theodossi, A.; Mendall, M. A.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA59
Academic Journal
Barrett's esophagus (BO) is a premalignant condition with histopathological evidence of dysplasia being the best marker of increased cancer risk. Of the 273 patients with histology confirmed BO, there were 45 patients with low grade dysplasia (LGD) and 2 patients with high grade dysplasia identified at some point. Authors undertook a retrospective analysis to determine the clinical outcome of patients with LGD. In the era of proton pump inhibitor therapy, about two third of cases of LGD in patients with underlying BO showed "regression" while none progressed to high grade dysplasia or carcinoma oesophagus.


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