TITLE

5-AMINOSALICYLIC ACIDS AND COLON RECTAL CANCER: A LARGE BRITISH EPIDEMIOLOGICAL STUDY

AUTHOR(S)
van Staa, T. P.; Cards, T.; Leufkens, H. G. M.; Logan, R.
PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA39
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article focuses on a study 5-aminosalicylic acids and colon rectal cancer in a large British epidemiological study. Medical records of general practitioners in the Great Britain, from the General Practice Research Database, were used to evaluate the risk of colorectal cancer (CRC) in patients with a history of IBD prescribed aminosalicylates (5-ASA). Of the 18,969 study patients, 100 developed CRC during 5-ASA exposure and most had a history of ulcerative colitis. These results support earlier work suggesting a possible preventative effect of 5-ASA in the development of CRC in ulcerative colitis.
ACCESSION #
13218966

 

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