TITLE

FINE MAPPING OF THE 5q31 RISK HAPLOTYPE IN CROHN'S DISEASE

AUTHOR(S)
Onnie, C. M.; Fisher, S. A.; Mirza, M.; Forbes, A.; Mansfield, J.; Sanderson, J.; Lewis, C. M.; Mathew, C. A.
PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA37
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article focuses on a study related to fine mapping of the 5q31 risk haplotype in crohn's disease (CD). Researchers have previously demonstrated an association between the 250 kb risk haplotype on 5q3l, CARD15 and early onset of CD. However, the true susceptibility gene on 5q31 has yet to be identified due to the high degree of linkage disequilibrium across this region observed in a Canadian cohort. Results of the case control analysis show that only SNP 2063 is significantly associated with CD.
ACCESSION #
13218957

 

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