Croft, N. M.; Paraszczuk, J.; Ali, E.; Wilson, J. W.; Jones, S. A.; Naik, S.; Sanderson, I. R.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA32
Academic Journal
Crohn's disease (CD) may arise in part from an aberrant immune response to intestinal flora. NOD2 is an intracellular lipopolysaccharide receptor involved in cellular response to bacterial products. The objective of this study is to determine whether clinical response to EN in children with CD associated with the 3020insC NOD2 polymorphism. Response to EN, and frequency of the NOD2 3020insCpolymorphism were similar to other reports. NOD2 3020insC allele status was not found to be associated with response to EN.


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