TITLE

IS THERE A RELATIONSHIP BETWEEN NOD2 POLYMORPHISM AND RESPONSE TO POLYMERIC ENTERAL FEED IN CHILDREN WITH CROHN'S DISEASE?

AUTHOR(S)
Croft, N. M.; Paraszczuk, J.; Ali, E.; Wilson, J. W.; Jones, S. A.; Naik, S.; Sanderson, I. R.
PUB. DATE
April 2004
SOURCE
Gut;Apr2004 Supplement 3, Vol. 53, pA32
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Crohn's disease (CD) may arise in part from an aberrant immune response to intestinal flora. NOD2 is an intracellular lipopolysaccharide receptor involved in cellular response to bacterial products. The objective of this study is to determine whether clinical response to EN in children with CD associated with the 3020insC NOD2 polymorphism. Response to EN, and frequency of the NOD2 3020insCpolymorphism were similar to other reports. NOD2 3020insC allele status was not found to be associated with response to EN.
ACCESSION #
13218939

 

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