THIOPURINE METHYL TRANSFERASE ACTIVITY PREDICTS BOTH TOXICITY AND CLINICAL RESPONSE TO AZATHIOPRINE IN INFLAMMATORY BOWEL DISEASE: THE LONDON IBD FORUM PROSPECTIVE STUDY
- Inflammatory Bowel Disease: Its Present and Its Future. Kirsner, Joseph B. // American Journal of Gastroenterology;Nov1989, Vol. 84 Issue 11, p1358
Discusses the developments in the treatment of inflammatory bowel disease (IBD) as of 2005. Experiment done to determine the treatment for IBD; Pathogenesis of IBD; Microbial cause of IBD.
- PROSPECTIVE STUDY OF THIOGUANINE NUCLEOTIDE MEASUREMENT DURING AZATHIOPRIPIE TREATMENT FOR INFLAMMATORY BOWEL DISEASE. // Gut;Apr2004 Supplement 3, Vol. 53, pA105
6-thioguanine nucleotides (IGN) are considered to be the active cytotoxic metabolite of azathioprine (ALA) although the exact mechanism action of the drug is by no means understood. Patients entering the study were treated with AZA at 2 mg/ kg for at least 6 months. Blood for TGN level was taken...
- A STUDY ON EFFICACY OF ORAL ZINC THERAPY FOR TREATMENT OF ACRODERMATITIS ENTEROPATHICA. Puri, Neerja // Our Dermatology Online / Nasza Dermatologia Online;Apr2013, Vol. 4 Issue 2, p162
Introduction: Acrodermatitis enteropathica (AE) is a disorder of zinc metabolism that occurs in one of two forms: an inborn (congenital) form and an acquired form. The inborn form of AE is a rare genetic disorder characterized by intestinal abnormalities that leads to inability to absorb zinc...
- Prevalencia de diferentes tipos de colitis en personas adultas mayores. Regino, William Otero; González, Angélica; Zuleta, Martín Gómez // Revista Colombiana de GastroenterologÃa;Jul2009, Vol. 24 Issue 3, p272
Introduction: Colitis is an inflammatory process of the colon with diverse etiologies, although clinical conditions and endoscopic examinations look similar. The attending physician should determine if the condition is acute (less than four weeks duration), or chronic (more than four weeks...
- Faecal S100A12 as a non-invasive marker distinguishing inflammatory bowel disease from irritable bowel syndrome. Kaiser, T.; Langhorst, J.; Wittkowski, H.; Becker, K.; Friedrich, A. W.; Rueffer, A.; Dobos, G. J.; Roth, J.; Foell, D. // Gut;Dec2007, Vol. 56 Issue 12, p1706
Objective: S100A12 is a pro-inflammatory protein that is secreted by granulocytes. S100A12 serum levels increase during inflammatory bowel disease (IBD). We performed the first study analysing faecal S100A12 in adults with signs of intestinal inflammation. Methods: Faecal S100A12 was determined...
- Letter to the editor regarding the report of Duboc et al: connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel disease. Jones, Mitchell L.; Martoni, Christopher J.; Prakash, Satya // Gut;Apr2013, Vol. 62 Issue 4, p654
A letter to the editor is presented in response to the article "Connectingdysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases" by H Duboc, S Rajca, D Rainteau et al. in the previous issue.
- A population frequency analysis of the FABP2 gene polymorphism in the Egyptian population. Salem, Abdelalim A. // Egyptian Journal of Medical Human Genetics;2009, Vol. 10 Issue 2, p178
Background: Intestinal fatty acid-binding protein (IFAPB) is expressed only in intestinal enterocytes. It may participate in the uptake, intracellular metabolism and/or transport of long chain fatty acids. A polymorphism at codon 54 in exon 2 of the FABP2 gene, which encodes for the IFAPB,...
- Correction: Hydroxyethyl Starch (HES 130/0.4) Impairs Intestinal Barrier Integrity and Metabolic Function: Findings from a Mouse Model of the Isolated Perfused Small Intestine. null, null // PLoS ONE;Apr2015, Vol. 10 Issue 4, p1
No abstract available.
- Insulin effect on glucose transport in thymocytes and splenocytes from rats with metabolic syndrome. Carbó, Roxana; Guarner, Verónica // Diabetology & Metabolic Syndrome;2010, Vol. 2 Issue 1, p1
Metabolic syndrome (MS) may comprise several clinical conditions such as obesity, diabetes and inflammatory disorders, which are characterized by metabolic imbalances. The study of glucose transport and regulation by insulin in lymphocytes is important, since the way they increase inflammation...