Japp, A.; Chui, M.; Waring, S.; Nicol, F.; Frad, M.
April 2004
Gut;Apr2004 Supplement 3, Vol. 53, pA27
Academic Journal
Altered autonomic function has been reported both in irritable bowel syndrome (IBS) and in anxiety and depression disorders and may contribute to abnormalities of gastrointestinal motility and visceral hypersensitivity. It is hypothesised that alterations in autonomic function may reflect increased central nervous system arousal associated with anxiety and depression as assessed using Hospital Anxiety and Depression (HAD) rating scale. It was found that patients with IBS demonstrate decreased parasympathetic and increased sympathetic responses to cardiovascular stimulation, which did not correlate with HAD ratings.


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